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Casino chronicles the lives of three characters: Sam ‘Ace’ Rothstein (Robert De Niro), a bookmaking wizard; Nicky Santoro (Joe Pesci), a Mafia underboss and Sam’s best friend; and Ginger McKenna (Sharon Stone), an ex-prostitute with a fondness for money. Sam is put in charge of the Tangiers, one of the biggest casinos in Las Vegas, while Nicky travels out there to give him protection. Everything should be perfect, especially as Sam has Ginger by his side. However, everything goes wrong as Nicky goes too far in his goal to become the main crime boss in Vegas and makes too many enemies, especially when he starts having an affair with Ginger.