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When it comes to romance, Missy’s (Cynthia Nixon) attitude has always been rather blasé. Her artistic career is flourishing, her spacious New York City loft is fabulous, and her relationship with a married man is totally uncomplicated. However, things get turned upside down when Missy meets Brat (Timothy Olyphant), a sweet genuine guy who shares her fondness for 70s sitcoms. Unfortunately, he is gay and he is also dating her friend, Spaz (Andy Dick). When Missy and Brat unexpectedly fall for each other, Missy begins to worry that she will lose her identity and her best friend. She also realises that no matter how far you run, true love always finds you.